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The role of reactive oxygen and antioxidant species in periodontal tissue destruction

Furthermore, the upregulation of defense-related proteins in pir1 may contribute to enhanced apoptosis, ultimately resulting in significantly improved resistance to bacterial blight

In this way, NRF2 drives the expression of various enzymes and signaling proteins involved in drug metabolism, antioxidant defense, and oxidative signaling, playing a crucial role in managing cellular responses to oxidative stress [7]

Mature Sertoli cells were enriched in Sertoli cell development, male gonad development, BMP signaling pathway, SMAD protein signal transduction, cellular response to corticotropin-releasing hormone stimulus and some GO terms related to development and proliferation (Fig