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5-Chloro-[6-[[(2,4,6-trimethylphenyl)amino]carbonyl]-2-benzothiazolyl]carbamic acid, 1,1-dimethylethyl ester (179D) and 7-Chloro-[6-[[(2,4,6-trimethylphenyl)amino]caxbonyl]-2-benzothiazolyl]carbamic acid, 1,1-dimethylethyl ester (180D) Example 181 Preparation of 2-Amino-5-hydroxy-N-[2,4,6-trimethylphenyl]-6-benzothiazolecarboxamide Example 182 Preparation of 5-tert-Butoxycarbonyloxy-[6-[[(2,4,6-trimethylphenyl)amino]carbonyl]-2-benzothiazolyl]carbamic acid, 1,1-dimethylethyl ester Example 183 Preparation of 2-[[[(1,1-Dimethylethyl)amino]carbonyl]amino]-N-(2,6-dimethylphenyl)-6-benzothiazolecarboxamide Alternative method A(Alt)

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Over time, this results in the accumulation of intracellular and extracellular metabolic debris