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For example, due to a genetic mutation that inhibits the synthesis of glutathione starting from its enzyme glutathione synthetase

Detection in professional sport can lead to suspension (WADA, 2023 Prohibited List)

It is important to note that current in vitro redox cycling detection is centred on indirect quantification of H 2 O 2 production and O 2 consumption rather than direct measurement of dynamic radical species over time 22,28

Avoid suppliers who lack clear labeling, offer very cheap prices, fail to disclose their manufacturing process or materials, or make exaggerated claims about product effectiveness

Thus, rigorous safety assessments of UA supplementation are essential