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The epigenetic-modified downregulation of LOXL1 protein mediates EMT in bladder epithelial cells exposed to benzo[a]pyrene and its metabolite BPDE

All media were sterilized by autoclaving as previously described, except those containing ABA, which was added after sterilization via filtration through a 0.22 m Millex membrane

10.1016/j.biopha.2022.113941 111 LouT.JiangW.XuD.ChenT.FuY

5.3 S-acylation in -cells S-acylation has been shown to be an important regulator of ion channels, vesicle trafficking, and small GTPAses, controlling many aspects of protein sorting, membrane localization, and lipid metabolism ( ATP channel activity is strongly modulated by S-acylation, which causes channel opening, counteracting the ability of ATP to close the channel ( 2+ channels ( 2+ influx and insulin exocytosis ( Figure 2 )

Therefore, further in-depth research should be performed to determine whether cysteine contributes to metabolic dysfunction related to breast cancer