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In patients with migraine with aura, SOD activity is significantly higher than in those without aura, although there is no significant correlation between SOD activity and the duration of migraine attacks (Tuncel et al., 2008

95% CI, 0.891.01

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However, you may find it takes longer to start working if you take them with a heavy meal

[40] The most common adverse effects of ROCK inhibitors are conjunctival hyperemia which is generally mild and short-lived