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Among the key causative agents, anthracyclines, such as doxorubicin (DOX), are particularly notable, as the severe cardiac damage they inducecharacterized by ventricular dilatation, interstitial fibrosis, and progression to HFsignificantly limits their clinical utility [73]

Anti-Aging Effects: Reduced NAD+ levels are associated with aging, and some studies suggest that boosting NAD+ may help slow down the aging process and protect against age-related diseases

The prepared nanodrug can achieve tumor-specific accumulation through EPR effect

Weaver et al., 2007

In addition, the role of other neurobiological markers, like neuroinflammation and neuroplasticity-related factors like BDNF, in mediating the effects of exercise on PTSD continues to be inadequately explored