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10.1083/jcb.200705180 [DOI] [PMC free article] [PubMed] [Google Scholar] Reddy A

Other drug options include Amantadine to help with tremors, Catechol-O-methyl transferase (COMT) inhibitors to prevent COMT from deactivating levodopa, Anticholinergic drugs to reduce tremors by blocking the neurotransmitter acetylcholine, and Adenosine A2A receptor antagonists, which can work in a similar manner to levodopa to reduce symptoms during levodopa off times

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If your clinic is inconveniently located, keeping up with these visits becomes a burden, and inconsistent follow-through can compromise your results