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The detailed sequences were 5-GAAGGAGGCUACUUCUAUAtt-3 (siRNA1), 5-GGAUCAUAUUUACAUGGAUtt-3 (siRNA2), and 5-GAGCCAUUGAAGAACAAUAtt-3 (siRNA3)

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Start use daily PM only, as the potent ingredients might take time for your skin to adjust, and you may experience some initial dryness, flakiness or irritation

AMPs have an amphipathic structure which enables cationic AMPs to interact specifically with the anionic bacterial cell membranes and enhance their permeability, causing cell death unaccompanied by affecting neutral eukaryotic cell membranes

Although current guidelines prioritize multimodal therapies based on phenotypic stratification, with pharmacological interventions primarily aimed at alleviating pain and lower urinary tract symptoms (LUTS) (202), select high-quality clinical studies have begun to explore the potential of targeted microenvironment regulation strategies, providing critical evidence for their feasibility