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When to Use Modifier 25: Five Conditions That Must All Be Met Modifier 25 is appropriate only when all five of the following conditions are present

Vitamin B12 deficiency in pregnancy can predispose women to pregnancy complications (such as preeclampsia or neural tube defects)

Her technique, skill and experience with acne scar subcision gave me complete confidence that I was in capable hands

The following may occur: It is important to remember that pregnant women who follow vegetarian diets (including some animal products such as milk and/or eggs) or strictly vegetarian diets (vegan) should take supplements and maintain adequate levels during pregnancy and breastfeeding, EVEN if they are asymptomatic

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