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Generation of mesenchymal stromal cells from urine-derived iPSCs of pediatric brain tumor patients

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Emodin can suppress cell growth through inducing cell cycle arrest at G0/G1, S and G2/M stages, such as G0/G1 arrest in NSCLC cells via hyaluronan synthase 2 (HAS2)-mediated signaling [461], and S and G2/M phases arrest in liver cancer (Hep G2) cells [456]

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Endothelial Cells : These cells form the lining of blood vessels within the thyroid gland

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This finding links 4HNE to ferroptosis, as evidenced by lipid peroxidation, iron accumulation, nuclear translocation of NRF2, decreased GPX4 protein levels, and increased expression of ferroptotic markers, confirming that 4HNE acts as an inducer of ferroptosis [54]

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