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Cerebral venous system and anatomical predisposition to high-altitude headache

(1987) Mar;137(3):530-3

More and more studies have found that the imbalance of oxidation and antioxidant, and the persistent damage to the brain by oxidative stress play an important role in the occurrence and development of schizophrenia

The upregulated DDX5 then recruits Protein Inhibitor of Activated STAT (PIAS)1, an inhibitory protein of STAT1, thereby blocking STAT1 phosphorylation and activation