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Inflammatory cytokines can inhibit the ability of blast-forming unit-erythroid or BFU-E to differentiate or alter the bone marrow environment, affecting erythropoiesis

In short, skin commensals maintain cutaneous homeostasis by balancing immune defense against pathogens and immune tolerance to commensal antigens

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Moreover, the decrease in NAD + /NADH ratio also inhibits the oxidation of acetaldehyde, the accumulation of which impairs mitochondria