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27 However, in humans, the EGFR inhibitor erlotinib largely failed to inhibit tumour growth in a Phase 2 trial of patients with advanced stage MPNST 28 (NCT00068367)

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While there are still significant challenges to overcome, the future of stem cell therapies and neural stem cell therapies offers an exciting alternative treatment not just to manage symptoms but also to slow or stop the progression of Parkinsons disease via dopamine cell replacement

The authors reveal that Ca2+-dependent ER luminal reduction is sensitive to GSH synthesis inhibition or cytosolic GSH dilution, indicating a glutathione-centered mechanism