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While glia-derived glutamine provides 50-60% of glutamate neurotransmitter, when the pathway is blocked with MeAIB excitatory transmission abruptly decreases but rapidly recovers, consistent with endogenous neuronal sources of glutamate neurotransmitter (15)

Interestingly, TSP-1 is also a well-documented regulator of the TGF superfamily in fibrotic diseases (Murphy-Ullrich and Suto, 2018)

After matching, the cohort consisted of 289 women and 578 men

After 30 min at RT, cells were washed and incubated with secondary Ab anti-Rabbit IgG FITC (Fisher Scientific 15303926)

doi:10.1021/acschembio.8b00767 ^ a b Han H.S., Kang G., Kim J.S., Choi B.H., Koo S.H