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GER can also occur de novo postoperatively due to altered functional anatomy of the GEJ caused by extensive mediastinal dissection

The dual receptor activity means that tirzepatide at a theoretically "equivalent" dose may feel significantly stronger

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3-phosphoglycerate generated from glycolysis in cancer cells is oxidized by PHGDH (phosphoglycerate dehydrogenase) to 3-phosphohydroxypyruvate, a precursor for de novo serine synthesis (65)