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these cells subsequently enter the arterial wall and promote atherosclerosis.95 In young adults who chronically used electronic cigarettes, FDG-PET CT showed increased uptake in the spleen and aortic wall compared with non-users, which is consistent with the engagement of the splenocardiac axis by the substances released by these devices.96 The effect on physical properties of the cardiovascular system come from a study of mice exposed to electronic cigarette vapours for 8 months (4 hours a day for 5 days a week, emulating an equivalent of 20 years of exposure in humans)

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While these associations are well established for traditional combustible tobacco products, more recent observational data reveals similar patterns for ENDS products, with the highest use rates witnessed in the lowest socioeconomic groups

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Episode title: Cigarettes, Cars and Wild, Wild Women PS I wish I had a recording of this background music on a loop