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Classification of Secondhand Smoke Exposure For secondhand smoke, as for any environmental factor that may be a cause of disease, the exposure assessment might encompass the time and place of the exposure, cumulative exposures, exposure during a particular time, or a recent exposure (Jaakkola and Jaakkola 1997

The lack of strong controls, independent testing, and consistent production techniques raises legitimate worries about the possible health consequences

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Inflammation seems to lead to the development of cancer because of the activities of leukocytes, including the production of proteins that alter the behavior of target cells (cytokines and chemokines), stimulation of blood vessel growth (angiogenesis) and tissue remodeling