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Description

When GSH levels fall below a certain threshold, GPX4 is no longer active, lipid ROS accumulate to toxic levels and cells undergo ferroptotic cell death

LeFauve, M

PLoS Pathog 6(6): e1000952

On the other hand, VB6 is necessary for the intracellular breakdown of glycogen, which is a vital source of energy for the activation of natural killer (NK) cells