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Apoptosis is the most common form of cell death in cancer, characterized by morphological changes like cell shrinkage, nuclear condensation, loss of adhesion to the extra-cellular matrix, and dynamic membrane blebbing [9,10,11,12]

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This is particularly important for oral forms of glutathione, which may be broken down in the digestive tract if taken with food

This work has been funded by the German Research Foundation (DFG) through grant LE LE2905/1-2 to LIL as part of the priority program 1710 Dynamics of Thiol-based Redox Switches in Cellular Physiology

On very rare occasions, more serious issues have been reported