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2.4 Site-specific conjugation To avoid the heterogeneous drug-to-antibody ratios (DAR) of stochastic lysine/cysteine conjugation, precision engineering is essential for both Onc-ADCs and ID-ADCs ( 2.5 Structural biology and computational design Structural biology provides the atomic-resolution framework necessary for rational ID-ADC design

Osteoporosis in Men The safety of Reclast in men with osteoporosis or osteoporosis secondary to hypogonadism was assessed in a two year randomized, multicenter, double-blind, active controlled group study of 302 men aged 25 to 86 years

Gut bacterial metabolism contributes to host global purine homeostasis

OCTOPUS: improving topology prediction by two-track ANN-based preference scores and an extended topological grammar

Olanzapine is an antipsychotic drug targeting the histamine 1 receptor, thereby reducing IL-6 generation ( Hydroxychloroquine and azithromycin were reported as effective anti-SARS-CoV-2 agents (Ohe et al., 2020