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Nonetheless, several limitations remain, including the predominantly preclinical nature of existing studies, significant variability in the bioavailability and dosing of phytochemicals such as curcumin and resveratrol, and the lack of standardized clinical protocols for implementing exercise and dietary interventions in oncology settings

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not carrying the genotype of a TSPO polymorphism (rs6971) associated with low binding to the TSPO radioligand [37]

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