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Despite the advancement in microsurgical techniques and some other interventions, the degree of regeneration and functional recovery of severe crushed or transected injuries of peripheral nerves are usually unsatisfactory due to their restricted intrinsic or spontaneous regenerative potential [3]

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Additional file 1: Table S5)

45,46,84 This is supported by studies in mice 85 and dogs

The peptide has a half-life of about 2 hours at room temperature (25C), meaning significant degradation occurs if left unrefrigeratedrefrigeration extends stability by slowing peptide bond hydrolysis