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These findings suggest that NNMT inhibition may modulate the metabolic responses to physical activity by altering cellular energy metabolism across multiple tissue types

[DOI] [PubMed] [Google Scholar] Glass 1961 Glass GB, Skeggs HR, Lee DH, Jones EL, Hardy WW

This configuration supports receptor-level interaction within adipocytes while minimizing affinity for the growth hormone receptor, distinguishing it from full-length GH and preventing downstream IGF-1 pathway activation