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Glutathione: Physiological and Clinical Relevance, 2012 The serine synthesis pathway converts 3PG to serine (Ser) through the activity of PHGDH, phosphoserine aminotransferase 1 (PSAT1), and phosphoserine phosphatase (PSPH)

In a series of 167 children with hematologic malignancy or aplastic anemia receiving dapsone for Pneumocystis (PCP) prophylaxis, 32 (19 percent) developed methemoglobinemia (median level: 9 percent, range 3.5 to 22 percent)