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In an in vitro PD model, this nanoplatform markedly attenuated oxidative stress, inhibited -syn aggregation, and restored cellular viability, underscoring its potential as a neuroprotective strategy (150)

VRK2 protects PC cells from ferroptosis by facilitating SLC7A11 trafficking Since SLC7A11-mediated cystine uptake and subsequent biosynthesis of GSH detoxifies phospholipid peroxidation and protects cells from ferroptosis [26], we speculated that VRK2-deficient PC cells, vulnerable to GSH inhibition is associated with ferroptosis

Under physiological conditions, native amylin spontaneously assembles into amyloid fibrils

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