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Mark AL, Correia ML, Rahmouni K, Haynes WG

This observed increase in CPT I expression by carnitine supplementation in this study could be secondary event following l-carnitine-induced decrease in malonyl-CoA production, the well-known potent inhibitor of CPT I

Future research should prioritize subtype-specific formulations for ischemic versus neuropathic DFUs, standardization of toxicity evaluation frameworks including reproductive and long-term biodistribution studies, and data-driven optimization of nanoparticle design through machine learning

Melatonin Reduces Hypoglycemia-Induced Neuronal Death in Rats

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