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As a final immune effector, NO generated by inducible NO synthase, kills pathogens and abnormal cells but may play a detrimental role by damaging normal host tissue and cells, especially when inducible NO synthase is persistently expressed [20]

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In addition, it should be taken into account that TCEP itself can suffer some decomposition in phosphate buffers at neutral pH ( AX Transformation Into DKP Implies a Loss of Reactivity and Antibacterial Potency DKP is a known metabolite of AX, considered to have lower or residual reactivity and bacteriostatic activity ( 1 H-NMR analysis of incubation mixtures containing equimolar amounts of DKP and butylamine revealed quantitative preservation of DKP (95% of the starting amount), thus confirming its lack of reactivity

In this process, free radicals steal electrons from lipids in the cell membrane, thereby leading to cell damage