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This circular RNA inhibited cell proliferation and promoted ferroptosis by sponging miR-335-3p, thereby upregulating ACSL4 expression [124]

Salim Kanaan, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The authors also note that long-term studies will be necessary to better understand potential toxicity and tissue-specific effects

Altenberg, B

Therefore, while our data demonstrate robust adipose tissue remodeling following Retatrutide treatment, they do not by themselves establish direct cell-autonomous effects on adipocytes or adipose-resident immune cells