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10.3389/fendo.2021.708838 23 LeiZYangLLeiYYangYZhangXSongQChenGLiuWWuHGuoJJT (2021b) High dose lithium chloride causes colitis through activating F4/80 positive macrophages and inhibiting expression of Pigr and Claudin-15 in the colon of mice

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Most users begin with: 200 mcg once daily (pre-bed) for recovery and sleep 200300 mcg twice daily (AM + pre-bed) for fat loss or general GH support 300 mcg 3x daily (AM + post-workout + pre-bed) for intensive recovery or performance stacking Higher doses may be tolerated, but studies show that GH release plateaus after ~300 mcg , and more is not always better