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Appropriate monitoring by a qualified healthcare provider is recommended throughout therapy

10.1016/j.ensci.2020.100256 121

The acetylated N-terminus slows renal clearance, extending the compound's half-life from approximately 90 minutes (GHK-Cu) to an estimated 68 hours (AHK-Cu) based on pharmacokinetic modeling

With simultaneous occlusion of both superior mesenteric vessels, i.e., the artery and the vein, both pathways, arterial and venous, are activated (Knezevic et al., 2021a)