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According to the previously accepted two-hit theory, the development of this disease occurs in two stages

During the acute phase of the disease, but also several months or years after successful antibiotic therapy, a significant proportion of patients develop symptoms of hypothalamic-pituitary insufficiency (62)

Clin Interv Aging 1:8191 Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, Anderson LJ, Fukuda K (2003) Mortality associated with influenza and respiratory syncytial virus in the United States

Relationship between chronic disturbance of 2,3-diphosphoglycerate metabolism in erythrocytes and Alzheimer disease

Tumors or other health condition : Some tumors can produce hormones that upset the delicate male-female hormone balance