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Correspondingly, considerable interest has been directed toward understanding the role and regulatory mechanisms of SLC7A11 in ferroptosis and tumor biology as well as therapeutically targeting SLC7A11 in cancer therapy

Insulin resistance in type 1 diabetes: pathophysiological, clinical, and therapeutic relevance

They share similarities but have significant differences

Its toxicity is mostly restricted to the oxidation of highly reactive thiol groups, some of which are functionally very important

Elevated markers of inflammation, such as C-reactive protein and various cytokines, have been reported in oncology patients (Mayland et al., 2005