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Therefore, we used the WGCNA algorithm to construct a gene co-expression network and modules for the microarray dataset GSE101702, calculated the expression variance of each gene, and screened the top 75% of absolute median deviation (MAD) and MAD value 0.01 genes for further analysis

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An example of a BSEP inhibitor is bosentan, a drug prescribed for pulmonary hypertension that includes a boxed warning for hepatotoxicity

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