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64 To investigate how the expression of PrP mutants impacted on Cu-mediated cell death, IF labelling of the mutant-expressing cells was combined with the Cell Event apoptotic assay

Furthermore, we showed that by treating distal lung fibroblasts from COPD patients with GHK, we can restore normal contractile function through re-organization of the actin cytoskeleton and up-regulation of integrin-1

Indeed, the SCCNVs could be produced by inducing senescence ex vivo in the cancer cells of patients and after several steps of purification, SCCNVs could be re-injected into the patients