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After the clearance of pathogens, the majority of effector T cells die through apoptosis and the remaining memory T (T mem ) cells are responsible for immunity upon re-exposure to the same pathogen

In contrast to the aforementioned findings, it was found that depletion of Gln or inhibition of glutamine metabolism in the tumor microenvironment leads to impaired T-cell function, which promotes immune escape of tumor cells and enhances cell proliferation, invasion, and metastasis

In recent years, the development of nanoparticle-based vaccines has benefitted from advances in material science that have led to improvements in antigen structure and stability, targeted vaccine delivery, and immunogenicity with good safety profiles

1 Supplementation targeting mitochondrial function, neuroinflammation, and gut integrity shows potential benefits

doi: 10.1080/00071660802337233 250 ParkT.MaL.GaoS.BuD.YuZ