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It has been shown that 5-HT7 receptor (agonist 8-OH-DPAT) activation could reverse mGluR-induced AMPA receptor internalization and correct excessive mGluR-LTD in hippocampal neurons of Fmr1 knockout mice, suggesting that 5-HT receptors may represent a novel therapeutic target for fragile X syndrome (Costa et al., 2012)

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e , Representative bright field images of shCtrl and shAMPK1 Huh7 cells with or without combo treatment for 48 h

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