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This specimen was later used for the immunohistochemical analyses

Neural Regen Res 13:11811182

LysoTracker Red staining revealed elevated lysosomal fluorescence intensity and upregulated ferroptosis markers (NCOA4, Fe 2+ ) in H9c2 cardiomyocytes subjected to I/R injury compared to controls, while Cur treatment significantly attenuated the I/R-induced increase in the LC3II/LC3I ratio and reduction in P62 protein expression

The result is the appearance of slowly increasing white patches, without any change in the skin texture