Regional coverage varies significantly, with high-level facilities in coastal and economic regions, while more limited access may exist in rural provinces
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Although brain uptake is modest early on, tracer binding in motor cortex and brainstem increases as disease advances, mirroring human ALS neuroinflammation and expanding diagnostic reach to neuromuscular involvement (142, 146, 147)

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a) Laboratory investigations: Including complete urine and stool analysis, Complete blood count including hemoglobin level, total leucocyte and platelet counts, Liver function tests including serum bilirubin, alanine aminotransferase, aspartate aminotransferase and albumin and renal function tests include blood urea and creatinine