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These pathways respond to changes in nutrient availability, protein misfolding, and other stressors, and can either promote or inhibit autophagy and ferroptosis depending on the specific context

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PTER inhibits amyloid--induced neuroinflammation in microglia by inactivating the NLRP3/caspase-1 inflammasome pathway and reduces the secretion levels of IL-6, IL-1 and TNF-, thereby attenuating the neuroinflammatory response, which would indicate that it could be a useful therapeutic strategy in neurodegenerative diseases (Li Q

Through animal experiments that extracellular vesicle miR-22-5p_R-1 inhibits the metabolic shift from mitochondrial respiration to glycolysis (MGS) in the trophoblast and suppresses trophoblastic EMT, increasing the likelihood of RM (Xiong et al., 2024)