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doi:10.1126/science.1210858

Bornstein SR, Schuppenies A, Wong ML, Licinio J

We then expressed these proteins in HEK293T cells to determine their effect on autophagy by detecting the protein levels of SQSTM1/p62 (a substrate receptor degraded by autophagy) and LC3-II (autophagosome membrane marker protein degraded through autophagy)