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One way to accomplish this is to inhibit NADPH oxidase (NOX), which is responsible for the formation of O 2 and, subsequently, the formation of ONOO

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Results Autoantibody-induced arthritis sensitizes multiple sensory neuron types before, during and after inflammation We used a cocktail of monoclonal pathogenic antibodies targeting cartilage, similar to RA autoantibodies, to induce arthritis in mice (cartilage autoantibody-induced arthritis model) 18

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Maintain aseptic handling to preserve compound integrity