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Substrate turnover can be detected by incubating intact lysosomes with CMA substrates in the absence of exogenous lysosomal protease inhibitors

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Although dietary interventions modulate the energetic substrate supply to tumors only to a limited extent, they offer significant ancillary benefits by imposing hormonal states that burden cancer metabolism, enhancing immune responses, and reducing inflammation

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When it comes to active dispersal, animals that are capable of free movement over large distances are ideal, typically moving through flying, swimming, or walking