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[3] [4] The only human data for BPC-157 come from a different direction entirely: early-phase clinical trials for inflammatory bowel disease conducted under the Pliva program (designations PL-10, PLD-116, and PL-14736)

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Exogenous 1,alpha,25-dihydroxyvitamin D3 (DHD3), the biologically active metabolite of vitamin D3, can inhibit different experimental models of autoimmune disease and can significantly ameliorate EAE, the mouse multiple sclerosis. [105, 106] Experiments conducted in vitro and in vivo with both DHD3 and its synthetic analogue Ro 63-2023 showed specific inhibition of the Th1 cytokines IL-12 and IFN-gamma

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Post-reconstitution, ensure the vial is sealed tightly, labeled with the date of mixing, and handled with sterile technique to maintain peptide integrity