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In its discovery-to-proof-of-concept work, it activated both receptors in vitro , improved glucose-dependent insulin secretion and glucose tolerance in animals, and in early human studies lowered fasting glucose and body weight

10.1161/CIRCULATIONAHA.124.071408 55 JiangM.BaiM.LeiJ.XieY.XuS.JiaZ.et al (2020)

Statements Author contributions BY: Methodology, Conceptualization, Writing review and editing, Software, Investigation, Writing original draft, Validation

In a study, AE was administered to zebrafish at a concentration of 0.01505 mg/mL for 72 h

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