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Regarding clinical outcomes in this subgroup, there were no major differences between the treatment and placebo groups

These mice were maintained in SPF units of the Animal Center of Shenzhen Peoples Hospital with a 12 h light cycle from 8 a.m

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Prior to eventual internalization by distant immune cells, the formation of MVs, which also contain important immune-cell receptors and inhibitory complement receptors, may contribute to an immune or tolerogenic microenvironment for MM cells in the bone marrow (BM) niche [25] [26]

Instrument performance was monitored regularly (approximately every 48 h) using a standard reference sample and an in-house Shiny QC application