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4.2 / vehicle, n = 9

Evaluation on clinical effect of long-term shexiang baoxin pill administration for treatment of coronary heart disease

By analyzing current studies on organelle-targeted PDT, we aim to deepen the understanding of PDTs mechanisms in inhibiting tumor growth and provide insights for its future clinical application

Beyond proteasomal targeting, non-canonical ubiquitin modifications, including K63-linked polyubiquitination, regulate signaling, endocytosis, kinase activity, and DNA damage responses, while mono- and multi-ubiquitination influence chromatin dynamics, DNA repair, and subcellular localization (Fig