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Its levels drop dramatically when the toxic load is large Detoxifies many xenobiotics Chelator of lead, mercury, cadmium, and arsenic Prevents neuropathy from chemotherapy Maintains reduced state of other antioxidants: vitamin C & E Supports numerous metabolic and biochemical reactions: DNA synthesis and repair Protein synthesis Prostaglandin synthesis Amino acid transportation Enzyme activation Glutathione is a powerful antioxidant made in the bodys cells, using amino acids: glutamine, glycine, and cysteine

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Beyond pH, another perspective posits that substrate concentration (e.g., H 2 O 2 level) and enzyme concentration are the key determinants driving the activity reversal of Pt nanozymes

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