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The event rate was so low that it was impossible to estimate the risk

Dunham-Snary KJ, Wu D, Sykes EA, Thakrar A, Parlow LRG, Mewburn JD, Parlow JL, Archer SL

The first to report on the development of PROTACs, marking a major innovation in the field by introducing chimeric molecules designed to induce targeted protein degradation through the Skp1CullinF box complex