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PMID: 28052092

Similar to cystinosin(7), F508 mutant is still partially functional if it traffics to the plasma membrane (50, 51)

Science (2006) 312(5778):13559

4d, S4)

Mutation driver genes In MDS patients, there are numerous mutation driver genes, which, through diverse mechanisms, lead to clonal outgrowth, myeloproliferation, and propagation of myelodysplastic hematopoiesis (Fig