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Individualized profiling and patient stratification Incorporating personalized medicine into amino acid metabolism research is critical for advancing breast cancer treatment strategies

First of all, cancer cells, unlike healthy eukaryotic cells that contain zwitterionic phosphatidylcholine and sphingomyelin in their membranes and therefore overall neutrally charged, 91 carry a net negative charge due to the elevated expression of anionic molecules such as phosphatidylserine (PS) and O-glycosylated mucins in their outer membrane leaflet, 92,93 which results in a greatly enhanced capacity for electrostatic interactions with AMPs

Schonberger, K

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Methods: This was a retrospective cohort study conducted using the TriNetX database and the US Collaborative Network, which includes healthcare information records from 60 healthcare organizations